ERAS Polyclonal Antibody

Background:
This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Signal Transduction, Stem Cells

Synonyms:
E ras, E-Ras, ecat5, Embryonic stem cell expressed Ras, Embryonic stem cell-expressed Ras, Eras, ES cell expressed Ras, GTPase ERas, Ha-Ras2, HRAS2, HRASP, MGC126691, MGC126693, OTTHUMP00000065857, RASE, Small GTPase protein E Ras, v Ha ras Harvey rat sarcoma viral oncogene homolog pseudogene, v Ha ras Harvey rat sarcoma viral oncogene homolog 2

Immunogen: Synthetic peptide of human ERAS

Swissprot: Q7Z444
Gene Accession: NP_853510

Calculated MW: 25 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.9 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-51073/sc-134860