ErbB-2/HER-2 Mouse mAb

Background:
ErbB 2 is a receptor tyrosine kinase of the ErbB 2 family. It is closely related instructure to the epidermal growth factor receptor. ErbB 2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.

Cellular localization: Cytoplasm. Nucleus and Cell membrane

Specificity: Human

Alternative Names:
CD340, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1

Immunogen: Synthetic Peptide

Isotype: Mouse Monoclonal IgG1

Concentration: 1mg/ml

Recommended dilutions: WB 1:2,000-4,000, IHC 1:200

Observed band: 138kDa

GeneID: 2064

Swiss-Prot No.: P04626

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

NOTE: For Research Use Only