ErbB2 (C-term), anti-human
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In stock
SKU
AC-AP7629b
Catalog Number: AC-AP7629b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1466
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1466
Applications: IHC-P, WB
Datasheet
Request Information
Background:
ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, althought neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
Other Names:
Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, MLN 19, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD340, ERBB2, HER2, MLN19, NEU, NGL
Target/Specificity:
This ErbB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1206-1236 amino acids from the C-terminal region of human ErbB2.
Antigen Region:
1206-1236
Antigen Type: Synthetic Peptide
Gene Name: ERBB2
Gene ID: 2064
Primary Accession: P04626
NCBI Accession: NP_001005862.1;NP_004439.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, althought neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
Other Names:
Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, MLN 19, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD340, ERBB2, HER2, MLN19, NEU, NGL
Target/Specificity:
This ErbB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1206-1236 amino acids from the C-terminal region of human ErbB2.
Antigen Region:
1206-1236
Antigen Type: Synthetic Peptide
Gene Name: ERBB2
Gene ID: 2064
Primary Accession: P04626
NCBI Accession: NP_001005862.1;NP_004439.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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