ERBB2 polyclonal, anti-human
€0.00
In stock
SKU
AC-AP7629e
Catalog Number: AC-AP7629e
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB14733
Applications: IHC-P-Leica, IF, FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB14733
Applications: IHC-P-Leica, IF, FC, WB
Datasheet
Request Information
Background:
ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
Other Names:
Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, MLN 19, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD340, ERBB2, HER2, MLN19, NEU, NGL
Target/Specificity:
This ErbB2 antibody is generated from rabbits immunized with human recombinant ErbB2 protein.
Antigen Type: Recombinant Protein
Gene Name: ERBB2
Gene ID: 2064
Primary Accession: P04626
NCBI Accession: NP_001005862.1;NP_004439.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
Other Names:
Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, MLN 19, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD340, ERBB2, HER2, MLN19, NEU, NGL
Target/Specificity:
This ErbB2 antibody is generated from rabbits immunized with human recombinant ErbB2 protein.
Antigen Type: Recombinant Protein
Gene Name: ERBB2
Gene ID: 2064
Primary Accession: P04626
NCBI Accession: NP_001005862.1;NP_004439.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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