ERBB2IP polyclonal, anti-human

Background:
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms: ERBIN, ERBB2IP, HEL-S-78, LAP2,

Cellular Location: Basolateral cell membrane Cell junction Nucleus membrane hemidesmosome

Immunogen:
Recombinant protein of human ERBB2IP

Gene Symbol: ERBB2IP

Gene ID: 55914

Swiss prot: Q96RT1

Calculated MW: 158kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.