ERC1 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants.

Synonyms:
ERC1, Cast2, ELKS, ERC-1, RAB6IP2

Immunogen: Recombinant fusion protein of human ERC1 (NP_829884.1).

Swissprot: Q8IUD2
Gene ID: 23085

Calculated MW: 81 kDa/108 kDa/113 kDa/124 kDa/128 kDa
Observed MW: 130 120 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.