ERCC2 antibody (clone 4G2-2A6), anti-human
€435.00
In stock
SKU
AC-AT1937a
Catalog Number: AC-AT1937a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB
Request Information AC-AT1937a">Request Information
Background:
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Other Names:
TFIIH basal transcription factor complex helicase XPD subunit, Basic transcription factor 2 80 kDa subunit, BTF2 p80, CXPD, DNA excision repair protein ERCC-2, DNA repair protein complementing XP-D cells, TFIIH basal transcription factor complex 80 kDa subunit, TFIIH 80 kDa subunit, TFIIH p80, Xeroderma pigmentosum group D-complementing protein, ERCC2, XPD, XPDC
Antigen Type:
Recombinant Protein
Gene Name: ERCC2
Gene ID: 2068
NCBI Accession: NP_000391.1;NP_001124339.1
Primary Accession: P18074
Other Accession: BC008346
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Other Names:
TFIIH basal transcription factor complex helicase XPD subunit, Basic transcription factor 2 80 kDa subunit, BTF2 p80, CXPD, DNA excision repair protein ERCC-2, DNA repair protein complementing XP-D cells, TFIIH basal transcription factor complex 80 kDa subunit, TFIIH 80 kDa subunit, TFIIH p80, Xeroderma pigmentosum group D-complementing protein, ERCC2, XPD, XPDC
Antigen Type:
Recombinant Protein
Gene Name: ERCC2
Gene ID: 2068
NCBI Accession: NP_000391.1;NP_001124339.1
Primary Accession: P18074
Other Accession: BC008346
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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