ERCC3 Polyclonal Antibody

Background:
This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism

Synonyms:
ERCC3, BTF2, GTF2H, RAD25, TFIIH, TTD2, XPB

Immunogen: Recombinant fusion protein of human ERCC3 (NP_000113.1).

Swissprot: P19447
Gene ID: 2071

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.