EREG polyclonal, anti-human

Quantity: 100 µg

Background:
Epiregulin (EPR) is a protein that in humans is encoded by the EREG gene. It is mapped to 4q13.3. This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). Also, it may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.

Description:
Rabbit IgG polyclonal antibody for Proepiregulin (EREG) detection. Tested with WB in Human.

Synonyms:
Epiregulin antibody, EPR antibody, ER antibody, Ereg antibody, EREG_HUMAN antibody, Proepiregulin antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E. coli-derived human EREG recombinant protein (Position: V60-L108). Human EREG shares 85.7% and 87.8% amino acid (aa) sequence identity with mouse and rat EREG, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.