ERI2 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP16538c
Catalog Number: AC-AP16538c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36064
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36064
Applications: WB
Datasheet
Request Information
Background:
EXOD1 (Exonuclease domain-containing protein 1), also known as ERI2 (ERI1 exoribonuclease 2), is a 691 amino acid protein that contains one exonuclease domain, which catalyzes the hydrolysis of unpaired or mismatched nucleotides. EXOD1 acitivity is dependent on the binding of two magnesium ions per subunit. There are four isoforms of EXOD1 that are produced as a result of alternative splicing events. The gene encoding EXOD1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Other Names:
ERI1 exoribonuclease 2, 31--, Exonuclease domain-containing protein 1, ERI2, EXOD1, KIAA1504
Target/Specificity:
This ERI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 444-472 amino acids from the Central region of human ERI2.
Antigen Region:
444-472
Antigen Type: Synthetic Peptide
Gene Name: ERI2
Gene ID: 112479
Primary Accession: A8K979
NCBI Accession: NP_001136197.1;NP_542394.2
Other Accession: NP_542394.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
EXOD1 (Exonuclease domain-containing protein 1), also known as ERI2 (ERI1 exoribonuclease 2), is a 691 amino acid protein that contains one exonuclease domain, which catalyzes the hydrolysis of unpaired or mismatched nucleotides. EXOD1 acitivity is dependent on the binding of two magnesium ions per subunit. There are four isoforms of EXOD1 that are produced as a result of alternative splicing events. The gene encoding EXOD1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Other Names:
ERI1 exoribonuclease 2, 31--, Exonuclease domain-containing protein 1, ERI2, EXOD1, KIAA1504
Target/Specificity:
This ERI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 444-472 amino acids from the Central region of human ERI2.
Antigen Region:
444-472
Antigen Type: Synthetic Peptide
Gene Name: ERI2
Gene ID: 112479
Primary Accession: A8K979
NCBI Accession: NP_001136197.1;NP_542394.2
Other Accession: NP_542394.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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