ERK 8 Polyclonal Antibody

Background:
MAPK15 (mitogen-activated protein kinase 15, ERK8) is a 544 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family (MAP kinase subfamily). MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPK15 functions as a catalytic kinase using ATP to produce ADP and a phosphoprotein. A TXY motif, containing one threonine and one tyrosine residue, activates the MAP kinases upon phosphorylation. MAPK15 is a ubiquitously expressed protein with highest expression found in lung and kidney.

Research Area: Signal Transduction

Synonyms:
ERK-7, ERK-8, ERK7, ERK8, Extracellular regulated kinase 8 delta, Extracellular signal regulated kinase 8, Extracellular signal-regulated kinase 7, Extracellular signal-regulated kinase 8, MAP kinase 15, MAPK 15, Mitogen activated protein kinase 15, MK15_HUMAN

Immunogen: Recombinant Human Mitogen-activated protein kinase 15 protien

Swissprot: Q8TD08

Purification Method: Affinity purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 2 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.