ERK1/2 (clone 1H4), anti-human, mouse, rat

Background:
MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

Synonyms: ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, p44-ERK1, p44-MAPK, P44ERK1, P44MAPK, PRKM3

Cellular Location: Cytoplasm Nucleus

Immunogen:
Synthetic Peptide

Gene Symbol: ERK1/2

Gene ID: 5595

Swiss prot: P27361/P28482

Calculated MW: 44/42kDa

Recommended dilution:
WB 1:1000-2000, IHC 1:100-200

Purity:
Saturated ammonium sulfate precipitation

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.