ERK1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Mitogen-activated protein kinase 3 is an enzyme that in humans is encoded by the MAPK3 gene.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases(ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. MAPK3 gene is mapped to human chromosome 16 by hybrid cell panel analysis.

Description:
Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase 3 (MAPK3) detection. Tested with WB, IHC-P, ICC in Human, Mouse, Rat.

Synonyms:
ERK 1 antibody, ERK antibody, ERK-1 antibody, ERK1 antibody, ERT 2 antibody, ERT2 antibody, Extracellular Signal Regulated Kinase 1 antibody, Extracellular signal related kinase 1 antibody, Extracellular signal-regulated kinase 1 antibody, HGNC6877 antibody, HS44KDAP antibody, HUMKER1A antibody, Insulin Stimulated MAP2 Kinase antibody, Insulin-stimulated MAP2 kinase antibody, MAP kinase 1 antibody, MAP kinase 3 antibody, MAP Kinase antibody, MAP kinase isoform p44 antibody, MAPK 1 antibody, MAPK 3 antibody, MAPK antibody, MAPK1 antibody, Mapk3 antibody, MGC20180 antibody, Microtubule Associated Protein 2 Kinase antibody, Microtubule-associated protein 2 kinase antibody, Mitogen Activated Protein Kinase 3 antibody, Mitogen-activated protein kinase 1 antibody, Mitogen-activated protein kinase 3 antibody, MK03_HUMAN antibody, OTTHUMP00000174538 antibody, OTTHUMP00000174541 antibody, p44 ERK1 antibody, p44 MAPK antibody, p44-ERK1 antibody, p44-MAPK antibody, P44ERK1 antibody, P44MAPK antibody, PRKM 3 antibody, PRKM3 antibody, Protein Kinase Mitogen Activated 3 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human ERK1(287-301aa KTKVAWAKLFPKSDS), identical to the related mouse and rat sequences.A synthetic peptide corresponding to a sequence in the middle region of human ERK1(287-301aa KTKVAWAKLFPKSDS), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.