Erk2 polyclonal, anti-human, mouse, rat antibody

Background:
Both p44 and p42 MAP kinases (Erk1 and Erk2) function in a protein kinase cascade that plays a critical role in the regulation of cell growth and differentiation. Activation of MAP kinases occurs thro µgh phosphorylation of threonine and tyrosine (202 and 204 of human MAP kinase [Erk1] or 183 and 185 of rat Erk2) at the sequence T*EY* by a single upstream MAP kinase kinase (MEK). Both kinases are known to weakly autophosphorylate on tyrosine.

Other Names:
ERK , ERK-2 , MAPK2 , PRKM2, Extracellular signal-regulated kinase 2, ERK2, Defective in aggregation protein C, MAP kinase 2, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, Extracellular signal-regulated kinase 2, ERK-2, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, MAP kinase isoform p42, p42-MAPK, ERT1.

Primary Accession: P28482.3

Concentration (mg/ml): 0.5 mg/ml