ERK4 polyclonal (C-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP7503a
Catalog Number: AC-AP7503a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0917
Applications: IHC-P, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0917
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The CMGC group consists of 60 kinases including the cyclin-dependent kinase (CDK) and close relatives family, the MAP kinase (ERK) family, the glycogen synthase kinase 3 (GSK3) family, and the Cdc2-like kinase (CLK) family.
Other Names:
Mitogen-activated protein kinase 4, MAP kinase 4, MAPK 4, Extracellular signal-regulated kinase 4, ERK-4, MAP kinase isoform p63, p63-MAPK, MAPK4, ERK4, PRKM4
Target/Specificity:
This ERK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-557 amino acids from the C-terminal region of human ERK4.
Antigen Region:
527-557
Antigen Type: Synthetic Peptide
Gene Name: MAPK4
Gene ID: 5596
Primary Accession: P31152
NCBI Accession: NP_002738.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The CMGC group consists of 60 kinases including the cyclin-dependent kinase (CDK) and close relatives family, the MAP kinase (ERK) family, the glycogen synthase kinase 3 (GSK3) family, and the Cdc2-like kinase (CLK) family.
Other Names:
Mitogen-activated protein kinase 4, MAP kinase 4, MAPK 4, Extracellular signal-regulated kinase 4, ERK-4, MAP kinase isoform p63, p63-MAPK, MAPK4, ERK4, PRKM4
Target/Specificity:
This ERK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-557 amino acids from the C-terminal region of human ERK4.
Antigen Region:
527-557
Antigen Type: Synthetic Peptide
Gene Name: MAPK4
Gene ID: 5596
Primary Accession: P31152
NCBI Accession: NP_002738.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
|---|
Write Your Own Review