ERLIN1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS72494
Background:
The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.
Alternative Name:
C10orf69,Erlin-1,KE04,KEO4,SPFH1,SPG62
Application Dilution: WB: 1:500 - 1:2000
Specificity: ERLIN1 polyclonal antibody detects endogenous levels of ERLIN1 protein.
Immunogen:
Recombinant protein of human ERLIN1
MW: ~ 39 kDa
Swis Prot.: O75477
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.
Alternative Name:
C10orf69,Erlin-1,KE04,KEO4,SPFH1,SPG62
Application Dilution: WB: 1:500 - 1:2000
Specificity: ERLIN1 polyclonal antibody detects endogenous levels of ERLIN1 protein.
Immunogen:
Recombinant protein of human ERLIN1
MW: ~ 39 kDa
Swis Prot.: O75477
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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