ERLIN1 Polyclonal Antibody

Background:
The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1, 4, 5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.

Synonyms:
ERLIN1, C10orf69, Erlin-1, KE04, KEO4, SPFH1, SPG62, erlin-1

Immunogen: Recombinant fusion protein of human ERLIN1 (NP_006450.2).

Swissprot: O75477
Gene ID: 10613

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.