ERP44 Polyclonal Antibody

Background:
ERP44 is a 406 amino acid protein that contains one thioredoxin domain, a motif that participates in various redox reactions throughout the cell. Localized to the lumen of the endoplasmic reticulum (ER), TXNDC4 functions to inhibit the activity of IP3R-I (inositol 1, 4, 5-triphosphate receptor, type 1) within calcium channels. In addition, TXNDC4 is thought to regulate oxidative protein folding within the ER and may be involved in retaining proteins.

Research Area: Cell biology, Metabolism, Signal transduction

Synonyms:
Endoplasmic reticulum resident protein 44, Endoplasmic reticulum resident protein 44 kDa, Endoplasmic reticulum resident protein ERp44, ER protein 44, ERp44, ERP44, KIAA0573, PDIA10, Protein disulfide isomerase family A, member 10, Thioredoxin domain containing 4 (endoplasmic reticulum), Thioredoxin domain containing protein 4, Thioredoxin domain-containing protein 4, UNQ532/PRO1075

Immunogen: Synthetic peptide of human ERP44

Swissprot: Q9BS26
Gene Accession: NP_055866

Calculated MW: 47 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:500-2000, IHC 1:25-100, ELISA 1:2000-5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-160886/sc-160887