ERVFRD-1 polyclonal, anti-human, mouse, rat

ERVFRD-1 polyclonal, anti-human, mouse, rat

€388.00
In stock
SKU
BS70416
Catalog Number: BS70416
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB

Datasheet
Background:
Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (PubMed:14694139).

Alternative Name:
ERVFRDE1, Syncytin-2, Syncytin 2, Syncytin2, Envelope polyprotein, HERV-FRD

Application Dilution: WB: 1:1000 - 1:4000

Specificity: ERVFRD-1 polyclonal antibody detects endogenous levels of ERVFRD-1 protein.

Immunogen:
Recombinant protein of human ERVFRD-1.

MW: ~ 60 kDa

Swis Prot.: P60508

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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