ERVFRD-1 polyclonal, anti-human, mouse, rat

Background:
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

Synonyms: ERVFRDE1, GLLL6191, HERV-FRD, HERV-W/FRD, UNQ6191, envFRD

Cellular Location: Cell membrane Single-pass membrane protein Virion

Immunogen:
Recombinant protein of human ERVFRD-1

Gene Symbol: ERVFRD-1

Gene ID: 405754

Swiss prot: P60508

Calculated MW: 60kDa

Recommended dilution:
WB 1:1000-4000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.