ERVW-1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
ERVW-1 is also known as ERVWE1. The human ERVWE1 locus is derived from a human endogenous retrovirus-W (HERV-W) provirus located on chromosome 7. This provirus has inactivating mutations in the gag and pol genes, but the envelope glycoprotein gene has been selectively preserved. The product of this gene, syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

Description:
Rabbit IgG polyclonal antibody for Syncytin-1 (ERVW-1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
Endogenous retrovirus group W member 1 antibody, ENV antibody, Envelope polyprotein gPr73 antibody, Enverin antibody, ENVW antibody, ERVWE1 antibody, HERV-7q antibody, HERV-7q Envelope protein antibody, HERV-W envelope protein antibody, HERV-W-ENV antibody, HERV-W_7q21.2 provirus ancestral Env polyprotein antibody, HERV7Q antibody, HERVW antibody, HERVWENV antibody, Syncytin 1 antibody, Syncytin antibody, Syncytin1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human ERVW-1(406-435aa YYVNQSGIVTEKVKEIRDRIQRRAEELRNT).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.