ERVW-1 Polyclonal Antibody

Background:
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta.

Research Area: Developmental Biology

Synonyms:
Endogenous retrovirus group W member 1, ENV, Envelope polyprotein gPr73, Enverin, ENVW, ERVWE1, HERV-7q, HERV-7q Envelope protein, HERV-W envelope protein, HERV-W-ENV, HERV-W_7q21.2 provirus ancestral Env polyprotein, HERV7Q, HERVW, HERVWENV, Syncytin 1, Syncytin, Syncytin1

Immunogen: Synthetic peptide of human ERVW-1

Swissprot: Q9UQF0
Gene Accession: NP_055405

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1.1 mg/mL
Dilution: IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.