ERVWE1 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP17034b
Background:
Many different human endogenous retrovirus (HERV) familiesare expressed in normal placental tissue at high levels, suggestingthat HERVs are functionally important in reproduction. This gene ispart of an HERV provirus on chromosome 7 that has inactivatingmutations in the gag and pol genes. This gene is the envelopeglycoprotein gene which appears to have been selectively preserved.The gene's protein product is expressed in the placentalsyncytiotrophoblast and is involved in fusion of thecytotrophoblast cells to form the syncytial layer of the placenta.The protein has the characteristics of a typical retroviralenvelope protein, including a furin cleavage site that separatesthe surface (SU) and transmembrane (TM) proteins which form aheterodimer. Alternatively spliced transcript variants encoding thesame protein have been found for this gene.
Other Names:
Syncytin-1, Endogenous retrovirus group W member 1, Env-W, Envelope polyprotein gPr73, Enverin, HERV-7q Envelope protein, HERV-W envelope protein, HERV-W_7q212 provirus ancestral Env polyprotein, Syncytin, Surface protein, SU, gp50, Transmembrane protein, TM, gp24, ERVW-1, ERVWE1
Gene Name: ERVW-1
Gene ID: 30816
Primary Accession: Q9UQF0
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Many different human endogenous retrovirus (HERV) familiesare expressed in normal placental tissue at high levels, suggestingthat HERVs are functionally important in reproduction. This gene ispart of an HERV provirus on chromosome 7 that has inactivatingmutations in the gag and pol genes. This gene is the envelopeglycoprotein gene which appears to have been selectively preserved.The gene's protein product is expressed in the placentalsyncytiotrophoblast and is involved in fusion of thecytotrophoblast cells to form the syncytial layer of the placenta.The protein has the characteristics of a typical retroviralenvelope protein, including a furin cleavage site that separatesthe surface (SU) and transmembrane (TM) proteins which form aheterodimer. Alternatively spliced transcript variants encoding thesame protein have been found for this gene.
Other Names:
Syncytin-1, Endogenous retrovirus group W member 1, Env-W, Envelope polyprotein gPr73, Enverin, HERV-7q Envelope protein, HERV-W envelope protein, HERV-W_7q212 provirus ancestral Env polyprotein, Syncytin, Surface protein, SU, gp50, Transmembrane protein, TM, gp24, ERVW-1, ERVWE1
Gene Name: ERVW-1
Gene ID: 30816
Primary Accession: Q9UQF0
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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