ESR1/ER monoclonal, anti-human
€0.00
In stock
SKU
AC-AM2006b
Catalog Number: AC-AM2006b
Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 415CT16.3.2.1
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 415CT16.3.2.1
Applications: WB
Datasheet
Request Information
Background:
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Other Names:
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1, ESR1, ESR, NR3A1
Target/Specificity:
This ESR1/ER antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 246-273 amino acids from human ESR1/ER.
Antigen Region:
246-273
Antigen Type: Synthetic Peptide
Gene Name: ESR1
Gene ID: 2099
Primary Accession: P03372
NCBI Accession: NP_000116.2;NP_001116212.1;NP_001116213.1;NP_001116214.1
Other Accession: P06211; Q29040; P19785; P49884; NP_000116.2; Q9TV98
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Other Names:
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1, ESR1, ESR, NR3A1
Target/Specificity:
This ESR1/ER antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 246-273 amino acids from human ESR1/ER.
Antigen Region:
246-273
Antigen Type: Synthetic Peptide
Gene Name: ESR1
Gene ID: 2099
Primary Accession: P03372
NCBI Accession: NP_000116.2;NP_001116212.1;NP_001116213.1;NP_001116214.1
Other Accession: P06211; Q29040; P19785; P49884; NP_000116.2; Q9TV98
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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