ESR1 isoform4 Antibody(C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP19656c
Background:
This gene encodes an estrogen receptor, a ligand-activatedtranscription factor composed of several domains important forhormone binding, DNA binding, and activation of transcription. Theprotein localizes to the nucleus where it may form a homodimer or aheterodimer with estrogen receptor 2. Estrogen and its receptorsare essential for sexual development and reproductive function, butalso play a role in other tissues such as bone. Estrogen receptorsare also involved in pathological processes including breastcancer, endometrial cancer, and osteoporosis. Alternative splicingresults in several transcript variants, which differ in their 5'UTRs and use different promoters.
Other Names:
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1, ESR1, ESR, NR3A1
Gene Name: ESR1
Gene ID: 2099
Primary Accession: P03372
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes an estrogen receptor, a ligand-activatedtranscription factor composed of several domains important forhormone binding, DNA binding, and activation of transcription. Theprotein localizes to the nucleus where it may form a homodimer or aheterodimer with estrogen receptor 2. Estrogen and its receptorsare essential for sexual development and reproductive function, butalso play a role in other tissues such as bone. Estrogen receptorsare also involved in pathological processes including breastcancer, endometrial cancer, and osteoporosis. Alternative splicingresults in several transcript variants, which differ in their 5'UTRs and use different promoters.
Other Names:
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1, ESR1, ESR, NR3A1
Gene Name: ESR1
Gene ID: 2099
Primary Accession: P03372
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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