ESR1 monoclonal, anti-human
€0.00
In stock
SKU
AC-AM1881a
Catalog Number: AC-AM1881a
Size: 80 µl, 400 µl
Isotype: mouse IgM,K
Clone Name: 194CT11.4.14
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgM,K
Clone Name: 194CT11.4.14
Applications: WB
Datasheet
Request Information
Background:
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Other Names:
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1, ESR1, ESR, NR3A1
Target/Specificity:
This ESR1 monoclonal antibody is generated from mouse immunized with ESR1 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: ESR1
Gene ID: 2099
Primary Accession: P03372
NCBI Accession: NP_000116.2;NP_001116212.1;NP_001116213.1;NP_001116214.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Other Names:
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1, ESR1, ESR, NR3A1
Target/Specificity:
This ESR1 monoclonal antibody is generated from mouse immunized with ESR1 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: ESR1
Gene ID: 2099
Primary Accession: P03372
NCBI Accession: NP_000116.2;NP_001116212.1;NP_001116213.1;NP_001116214.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
| Is Featured? | No |
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