ESR1 polyclonal, anti-human, mouse, rat

Background:
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling.

Synonyms: ER, ESR, ESRA, ESTRR, Era, NR3A1

Cellular Location: Cell membrane Cytoplasm Cytoplasmic side Cytoplasmic side Golgi apparatus Nucleus Peripheral membrane protein Single-pass type I membrane protein

Immunogen:
A synthetic peptide of human ESR1

Gene Symbol: ESR1

Gene ID: 2099

Swiss prot: P03372

Calculated MW: 66kDa

Recommended dilution:
IHC 1:50

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.