ESR2 antibody (clone 3F3), anti-human
€435.00
In stock
SKU
AC-AT1950a
Catalog Number: AC-AT1950a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, E
Request Information AC-AT1950a">Request Information
Background:
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
Other Names:
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2, ESR2, ESTRB, NR3A2
Antigen Type:
Recombinant Protein
Gene Name: ESR2
Gene ID: 2100
NCBI Accession: NP_001035365.1;NP_001201831.1;NP_001201832.1;NP_001258805.1;NP_001258806.1;NP_001428.1
Primary Accession: Q92731
Other Accession: NM_001437
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
Other Names:
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2, ESR2, ESTRB, NR3A2
Antigen Type:
Recombinant Protein
Gene Name: ESR2
Gene ID: 2100
NCBI Accession: NP_001035365.1;NP_001201831.1;NP_001201832.1;NP_001258805.1;NP_001258806.1;NP_001428.1
Primary Accession: Q92731
Other Accession: NM_001437
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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