ESR2 monoclonal, anti-human

ESR2 monoclonal, anti-human

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In stock
SKU
AC-AM2112b
Catalog Number: AC-AM2112b
Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 555CT18.5.5
Applications: WB
Datasheet

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Background:
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

Other Names:
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2, ESR2, ESTRB, NR3A2

Target/Specificity:
This ESR2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 369-397 amino acids from human ESR2.

Antigen Region:
369-397

Antigen Type: Synthetic Peptide

Gene Name: ESR2
Gene ID: 2100
Primary Accession: Q92731
NCBI Accession: NP_001035365.1;NP_001201831.1;NP_001201832.1;NP_001258805.1;NP_001258806.1;NP_001428.1
Other Accession: Q62986; Q9XSW2; Q9PTU5; Q9XSB5; NP_001428; Q9TU15
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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