EST3 Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics| such as cocaine and heroin| and endogenous substrates with ester| thioester| or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism| and may play a role in the blood-brain barrier system. This gene is expressed in several tissues| particularly in colon| trachea and in brain| and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported| but the biological validity and/or full-length nature of some variants have not been determined.

Research Area: Metabolism, Signal transduction

Synonyms: EST3, Carboxylesterase 3, EC 3.1.1.1, Liver carboxylesterase 31 homolog)

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year