Estrogen Receptor alpha (Marker of Estrogen Dependence) (cloneESR1/420), anti-human

Estrogen Receptor alpha (Marker of Estrogen Dependence) (cloneESR1/420), anti-human

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In stock
SKU
ARP-24-2099-MSM4
Catalog Number: 24-2099-MSM4
Size: 100 µl, 0.5 ml, 1 ml
Isotype: Mouse IgG2a
Decription:
This monoclonal antibody is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this monoclonal antibody is mapped between aa300-550. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Synonyms: Estrogen Receptor alpha delta 4*5,6,7*/654 isoform, Estrogen Receptor alpha delta 4 +49 isoform, Nuclear receptor subfamily 3 group A member 1

Clone: ESR1/420

Isotype: Mouse IgG2a

Immunogen: Recombinant human ESR1 protein (aa290-560)

Reactivity: human. Others not known.

Form: Purified, in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Applications: Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Immunofluorescence (1-2ug/ml)
Western Blotting (0.5-1.0ug/ml for 2 hours at Room Temp)
Optimal dilution for a specific application should be determined.

Reactivity: MCF-7 Cells or Breast Cancers.

Concentration: 0.2mg/ml

Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
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