ETBR Polyclonal Antibody

Background:
endothelin receptor type B(EDNRB) Homo sapiens The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016],

Alternative Names:
Endothelin B receptor (ET-B) (ET-BR) (Endothelin receptor non-selective type)

Immunogen: Synthesized peptide derived from ETBR at AA range: 31-80

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 50

GeneID: EDNRB

Storage: -20°C/1 year

NOTE: For Research Use Only