ETFA polyclonal (C-term), anti-human, mouse

ETFA polyclonal (C-term), anti-human, mouse

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In stock
SKU
AC-AP11127b
Catalog Number: AC-AP11127b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20724
Applications: IHC-P, FC, WB
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Background:
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.

Other Names:
Electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF, ETFA

Target/Specificity:
This ETFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the C-terminal region of human ETFA.

Antigen Region:
276-304

Antigen Type: Synthetic Peptide

Gene Name: ETFA
Gene ID: 2108
Primary Accession: P13804
NCBI Accession: NP_000117.1;NP_001121188.1
Other Accession: P13803; Q99LC5; Q8HXY0; Q2KJE4; NP_000117.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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