ETS1 / (clone ETS1/1282), anti-human

Background:
ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator. The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells. ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.

Other Names:
Avian erythroblastosis virus E26 (v ets) oncogene homolog 1; ETS1; EWSR2; p54; v-ets erythroblastosis virus E26 oncogene homolog 1

Antigen Type:
Recombinant protein

Gene Name: ETS1
Gene ID: 2113
Primary Accession: P14921
Other Accession: 369438