EVPL polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. This gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against the encoded protein.

Synonyms: EVPK

Cellular Location: Cell junction Cornified envelope Cytoplasm cytoskeleton desmosome

Immunogen:
Recombinant protein of human EVPL

Gene Symbol: EVPL

Gene ID: 2125

Swiss prot: Q92817

Calculated MW: 232kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.