EWSR1 Picoband™ (clone 4B4), anti-human, mouse, primate
€455.00
In stock
SKU
AC-ABO14820
Catalog Number: AC-ABO14820
Size: 100 µg
Isotype: Mouse
Applications: WB, IHC
Datasheet
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Size: 100 µg
Isotype: Mouse
Applications: WB, IHC
Datasheet
Request Information
Description: Anti-EWSR1 Antibody Picoband™ (monoclonal, 4B4) . Tested in IHC, WB applications. This antibody reacts with Human, Monkey, Mouse.
Protein Function:
Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.
Other Names: RNA-binding protein EWS, EWS oncogene, Ewing sarcoma breakpoint region 1 protein, EWSR1, EWS
Clone Name(s):
Clone: 4B4
Subcellular Localization: Nucleus
Tissue Specificity: Ubiquitous.
Gene ID: 2130
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human EWSR1, different from the related mouse sequence by one amino acid.
Calculated MW: 68478
Format: Lyophilized
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Protein Function:
Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.
Other Names: RNA-binding protein EWS, EWS oncogene, Ewing sarcoma breakpoint region 1 protein, EWSR1, EWS
Clone Name(s):
Clone: 4B4
Subcellular Localization: Nucleus
Tissue Specificity: Ubiquitous.
Gene ID: 2130
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human EWSR1, different from the related mouse sequence by one amino acid.
Calculated MW: 68478
Format: Lyophilized
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
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