EXD2 Polyclonal Antibody

Background:
Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
4930539P14Rik, C14orf114, C85658, DKFZp781A0133, DKFZp781L15100, Exd2, EXD2, EXDL2, Exonuclease 3''-5'' domain-containing protein 2, Exonuclease 3''-5'' domain-like-containing protein 2, exonuclease 3'-5' domain-like 2, FLJ10738, RGD1311087

Immunogen: Fusion protein of human EXD2

Swissprot: Q9NVH0
Gene Accession: BC001962

Calculated MW: 70 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.