EXOSC1 polyclonal, anti-human

Background:
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants.

Alternative Name:
p13, CSL4, SKI4, Csl4p, Ski4p, CGI-108,

Application Dilution: WB : 1:500 - 1:2000

Specificity: EXOSC1 polyclonal antibody detects endogenous levels of EXOSC1 protein.

Immunogen:
Recombinant protein of human EXOSC1

MW: Predicted band size: 21 kDa, Observed band size: Refer to Figures

Swis Prot.: Q9Y3B2

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.