EYA3 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70978
Background:
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.
Alternative Name:
Eyes absent homolog 3
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: EYA3 polyclonal antibody detects endogenous levels of EYA3 protein.
Immunogen:
Recombinant protein of human EYA3.
MW: ~ 63 kDa
Swis Prot.: Q99504
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.
Alternative Name:
Eyes absent homolog 3
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: EYA3 polyclonal antibody detects endogenous levels of EYA3 protein.
Immunogen:
Recombinant protein of human EYA3.
MW: ~ 63 kDa
Swis Prot.: Q99504
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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