EYA3 Polyclonal Antibody

Background:
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.

Research Area: Epigenetics and Nuclear Signaling, Signal Transduction, Stem Cells

Synonyms:
EYA3

Immunogen: Recombinant fusion protein of human EYA3 (NP_001981.2).

Swissprot: Q99504
Gene ID: 2140

Calculated MW: 48 kDa/56 kDa/57 kDa/58 kDa/62 kDa
Observed MW: 57 kDa/58 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.