Ezh2 (Phospho-Thr311) Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes| which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein| the VAV1 oncoprotein| and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

Research Area: Epigenetics and nuclear signaling

Synonyms: Ezh2 , Thr311, Histone-lysine N-methyltransferase EZH2, EC 2.1.1.43, ENX-1, Enhancer of zeste homolog 2, Lysine N-methyltransferase 6

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year