EZR polyclonal, anti-human, mouse, rat

Background:
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Synonyms: CVIL, CVL, HEL-S-105, VIL2

Cellular Location: Apical cell membrane Cell projection Cytoplasm Cytoplasmic side Peripheral membrane protein cell cortex cytoskeleton microvillus membrane ruffle membrane

Immunogen:
Recombinant protein of human EZR

Gene Symbol: EZR

Gene ID: 7430

Swiss prot: P15311

Calculated MW: 69kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-100, IP 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.