EZR Polyclonal Antibody

Background:
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Research Area: Cancer, Signal Transduction

Synonyms:
Villin 2 ezrin, CVIL, CVL, Cytovillin 2, Cytovillin, DKFZp762H157, Epididymis secretory protein Li 105, EZR, EZRI, Ezrin, FLJ26216, HEL S 105, MGC1584, p81, VIL 2, VIL2, Villin 2 (ezrin), Villin 2, Villin-2, Villin2

Immunogen: Recombinant protein of human EZR

Swissprot: P15311
Gene Accession: BC013903

Calculated MW: 69 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6409/sc-6407/sc-32918/sc-20773