EZR Polyclonal Antibody

Background:
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

Research Area: Cancer, Signal Transduction

Synonyms:
Villin 2 ezrin, CVIL, CVL, Cytovillin 2, Cytovillin, DKFZp762H157, Epididymis secretory protein Li 105, EZR, EZRI, Ezrin, FLJ26216, HEL S 105, MGC1584, p81, VIL 2, VIL2, Villin 2 (ezrin), Villin 2, Villin-2, Villin2

Immunogen: Synthesized peptide derived from the C-terminal region of human Ezrin

Swissprot: P15311

Calculated MW: 69 kDa
Observed MW: 70 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.