F11 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP11568c
Background:
This gene encodes coagulation factor XI of the bloodcoagulation cascade. This protein is present in plasma as azymogen, which is a unique plasma coagulation enzyme because itexists as a homodimer consisting of two identical polypeptidechains linked by disulfide bonds. During activation of the plasmafactor XI, an internal peptide bond is cleaved by factor XIIa (orXII) in each of the two chains, resulting in activated factor XIa,a serine protease composed of two heavy and two light chains heldtogether by disulfide bonds. This activated plasma factor XItriggers the middle phase of the intrisic pathway of bloodcoagulation by activating factor IX. Defects in this factor lead toRosenthal syndrome, a blood coagulation abnormality. [provided byRefSeq].
Other Names:
Coagulation factor XI, FXI, Plasma thromboplastin antecedent, PTA, Coagulation factor XIa heavy chain, Coagulation factor XIa light chain, F11
Gene Name: F11
Gene ID: 2160
Primary Accession: P03951
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes coagulation factor XI of the bloodcoagulation cascade. This protein is present in plasma as azymogen, which is a unique plasma coagulation enzyme because itexists as a homodimer consisting of two identical polypeptidechains linked by disulfide bonds. During activation of the plasmafactor XI, an internal peptide bond is cleaved by factor XIIa (orXII) in each of the two chains, resulting in activated factor XIa,a serine protease composed of two heavy and two light chains heldtogether by disulfide bonds. This activated plasma factor XItriggers the middle phase of the intrisic pathway of bloodcoagulation by activating factor IX. Defects in this factor lead toRosenthal syndrome, a blood coagulation abnormality. [provided byRefSeq].
Other Names:
Coagulation factor XI, FXI, Plasma thromboplastin antecedent, PTA, Coagulation factor XIa heavy chain, Coagulation factor XIa light chain, F11
Gene Name: F11
Gene ID: 2160
Primary Accession: P03951
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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