F2R Polyclonal Antibody

Background:
Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

Research Area: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
CF2R, Coagulation factor II (thrombin) receptor, Coagulation factor II receptor, F2R, HTR, PAR 1, PAR-1, PAR1, PAR1, Protease activated receptor 1, Proteinase activated receptor 1, Proteinase-activated receptor 1, Thrombin receptor, TR

Immunogen: Synthetic peptide of human F2R

Swissprot: P25116
Gene Accession: NP_001983

Calculated MW: 47 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-8202/sc-8203/sc-5605