F3 antibody (clone 4G4), anti-human
€435.00
In stock
SKU
AC-AT1979a
Catalog Number: AC-AT1979a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IP, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IP, E
Request Information AC-AT1979a">Request Information
Background:
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.
Other Names:
Tissue factor, TF, Coagulation factor III, Thromboplastin, CD142, F3
Antigen Type:
Recombinant Protein
Gene Name: F3
Gene ID: 2152
NCBI Accession: NP_001171567.1;NP_001984.1
Primary Accession: P13726
Other Accession: BC011029
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.
Other Names:
Tissue factor, TF, Coagulation factor III, Thromboplastin, CD142, F3
Antigen Type:
Recombinant Protein
Gene Name: F3
Gene ID: 2152
NCBI Accession: NP_001171567.1;NP_001984.1
Primary Accession: P13726
Other Accession: BC011029
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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