F9 antibody (clone 2C9), anti-human
€435.00
In stock
SKU
AC-AT1981a
Catalog Number: AC-AT1981a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IP, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IP, E
Request Information AC-AT1981a">Request Information
Background:
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.
Other Names:
Coagulation factor IX, Christmas factor, Plasma thromboplastin component, PTC, Coagulation factor IXa light chain, Coagulation factor IXa heavy chain, F9
Antigen Type:
Recombinant Protein
Gene Name: F9
Gene ID: 2158
NCBI Accession: NP_000124.1
Primary Accession: P00740
Other Accession: NM_000133
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.
Other Names:
Coagulation factor IX, Christmas factor, Plasma thromboplastin component, PTC, Coagulation factor IXa light chain, Coagulation factor IXa heavy chain, F9
Antigen Type:
Recombinant Protein
Gene Name: F9
Gene ID: 2158
NCBI Accession: NP_000124.1
Primary Accession: P00740
Other Accession: NM_000133
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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