FA10 Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
Catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.|Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va| calcium and phospholipid during blood clotting.|online information:Factor X entry|PTM:N- and O-glycosylated.|PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway)| or by factor VIIa (in the extrinsic pathway).|PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.|PTM:The vitamin K-dependent| enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.|Belongs to the peptidase S1 family.|Contains 1 Gla (gamma-carboxy-glutamate) domain.|Contains 1 peptidase S1 domain.|Contains 2 EGF-like domains.|subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds.|tissue specificity:Plasma; synthesized in the liver.|

Research Area: Cardiovascular

Synonyms: FA10 , light chain, Cleaved-Arg179, Coagulation factor X, EC 3.4.21.6, Stuart factor, Stuart-Prower factor, Factor X light chain, Factor X heavy chain, Activated factor Xa heavy chain,

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year