FAAP24 Polyclonal Antibody

Background:
Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
C19ORF40, C19orf40 chromosome 19 open reading frame 40, FAAP24, Fanconi anemia-associated protein 24 kDa, Fanconi anemia-associated protein of 24 kDa, FAP24, MGC32020

Immunogen: Synthetic peptide of human FAAP24

Swissprot: Q9BTP7
Gene Accession: NP689479

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.84 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.